Frankly, I'd be more worried about losing the screw. I can't tell from the photo, so it isn't clear if the screw is in a threaded portion of the crampon metal, or if there is a lock-nut somewhere.
I have an "older" set of Stubai crampons that have a screw and a pin that fits through a hole behind the screw. I never had the screw loosen; but the crampons are essentially non-adjustable once you were out on a trip, unless you carry a toolkit and are dexterous when your fingers are cold. If your boots are very stiff, your "at home" adjustment is probably the only one you'll need.
However, I've adjusted my crampons in the field many times, when I was wearing less-stiff boots.