It's the easiest route to the summit but it's hard because you must cross a long ramp of scree.
Cardaño de Abajo is in the road between Velilla del Río Carrión y Cervera de Pisuerga.
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In the main square of Cardaño de Abajo (1.300m) you take a track to left side from the source continuing to a curve. You take a forest track (with signal of prohibited to cars) walking for 2km until a big curve when you can see some cairns in right side.
You walk in the hillside following cairns turning to left side in direction to the evident entry between both summits of Espigüete (the main summit is in left side). You're now in the worse part of the route, a big ramp of scree, and you must walk with a lot of patience (it's advisable the use of walking poles). The middle part has small rocky terraces walking to left side until a path in the ground. You reach finally the col at right side of the summit with hard effort. Your reward is waiting in left side, walking a few of meters across a nice ridge. The summit has excellent views to all places around it.
Water, good boots and walking poles in summer.
In winter it's not a normal route, the people prefer North route because the snow is in better conditions but if you want climb South route you will need crampons and ice-axe because is steepy (30-35º).