RyanBr, I just went throughout the same thing and it seems we are the same size. After going from a 43.5 all the way to 45's, I thought the same thing and found that the 45 was too big after a few days of break-in and themo-molding. These ended up with 1/2" heel room, slippage and lift even with thick inserts, ortho's and thick socks. The 45 should will fit a size 12 foot. The Spanitik should fit the same size as your normal show size or La Sportiva Boot size. In my case a 44 Nepal. More athttp://coldthistle.blogspot.com/
just look back in archives.